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The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It is closely related to the cannabinoid receptor 1 (CB1), which is largely responsible for the efficacy of endocannabinoid-mediated presynaptic-inhibition, the psychoactive properties of tetrahydrocannabinol (THC), the active agent in cannabis, and ...
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Cannabinol ( CBN) is a mildly psychoactive cannabinoid (e.g., CBD) that acts as a low affinity partial agonist at both CB1 and CB2 receptors. This activity at CB1 and CB2 receptors constitutes interaction of CBN with the endocannabinoid system (ECS).
In 2011, Free Shipping Day became a billion-dollar shopping holiday with $1.072 billion in sales, followed by $1.01 billion during Free Shipping Day 2012. In 2013, Knowles changed the format of Free Shipping Day to only include merchants that could waive all minimum order requirements and guarantee delivery by Christmas Eve.
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