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The plasma membrane monoamine transporter ( PMAT) is a low-affinity monoamine transporter protein which in humans is encoded by the SLC29A4 gene. [1] It is known alternatively as the human equilibrative nucleoside transporter-4 (hENT4). It was discovered in 2004 [2] and has been identified as a potential alternate target for treating various ...
Monoamine transporters ( MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters. The three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible for the reuptake of their ...
Neurotransmitter transporter. Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons. Their primary function is to carry neurotransmitters across these membranes and to direct their further transport to specific intracellular locations. There are more than twenty types of ...
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons.It transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephrine, and histamine – into the vesicles, which release the neurotransmitters into synapses, as chemical messages to postsynaptic neurons.
Distribution of VMAT2 in the human brain. The solute carrier family 18 member 2 ( SLC18A2) also known as vesicular monoamine transporter 2 ( VMAT2) is a protein that in humans is encoded by the SLC18A2 gene. [5] SLC18A2 is an integral membrane protein that transports monoamines —particularly neurotransmitters such as dopamine, norepinephrine ...
PMAT. PMAT may refer to: Plasma membrane monoamine transporter (PMAT) Four phases of mitosis: prophase, metaphase, anaphase, and telophase. Prophase: Chromatin into chromosomes, the nuclear envelope break down, chromosomes attach to spindle fibres by their centromeres. Metaphase: Chromosomes line up along the metaphase plate (centre of the cell).
Uniporter. Uniporters, also known as solute carriers or facilitated transporters, are a type of membrane transport protein that passively transports solutes (small molecules, ions, or other substances) across a cell membrane. [1] It uses facilitated diffusion for the movement of solutes down their concentration gradient from an area of high ...
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