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DMG-PEG 2000. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines, [1] and in particular forms part of the drug delivery ...
PEGylation is the process of attaching the strands of the polymer PEG to molecules, most typically peptides, proteins, and antibody fragments, that can improve the safety and efficiency of many therapeutics. [9] [10] It produces alterations in the physiochemical properties including changes in conformation, electrostatic binding, hydrophobicity ...
Demon Music Group Limited (DMG; formerly Object Enterprises Limited from 1982–1991 and Music Collection International Limited from 1991–2000) is a record company owned by BBC Studios that is mainly concerned with back-catalogue rights and re-issuing recordings as compilations on physical media (CDs and vinyl) via supermarkets and specialist stores.
Dimethylglycine is an essential amino acid, which means that the body cannot make this chemical on its own. It must be consumed in the diet. It is found in grains and meats and can also be taken ...
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Polyethylene glycol ( PEG; / ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, - ˈɛθɪl -, - ˌkɔːl /) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide ( PEO) or polyoxyethylene ( POE ), depending on its molecular weight. The structure of PEG is ...
Distearoylphosphatidylcholine is a phosphatidylcholine, a kind of phospholipid. It is a natural constituent of cell membranes, eg. soybean phosphatidylcholines are mostly different 18-carbon phosphatidylcholines (including minority of saturated DSPC), and their hydrogenation results in 85% DSPC. [1]
SM-102 is a synthetic amino lipid which is used in combination with other lipids to form lipid nanoparticles. [1] These are used for the delivery of mRNA-based vaccines, [2] [3] [4] and in particular SM-102 forms part of the drug delivery system for the Moderna COVID-19 vaccine. [5] [6] [7]
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