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The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. [1] The UPDRS is made up of these sections: [2] Part I: evaluation of mentation, behavior, and mood
Parkinsonian gait (or festinating gait, from Latin festinare [to hurry]) is the type of gait exhibited by patients with Parkinson's disease (PD). [2] It is often described by people with Parkinson's as feeling like being stuck in place, when initiating a step or turning, and can increase the risk of falling. [3]
Parkin is a 465-amino acid residue E3 ubiquitin ligase, a protein that in humans and mice is encoded by the PARK2 gene. [5] [6] Parkin plays a critical role in ubiquitination – the process whereby molecules are covalently labelled with ubiquitin (Ub) and directed towards degradation in proteasomes or lysosomes.
Parkinson’s disease is a neurological condition that can affect several areas of the brain. The area it affects the most is known as the substantia nigra, which is involved with movement ...
Parkinson’s disease is a progressive neurological disorder. It causes issues like tremor, muscle stiffness, and slow movements. It affects nearly 1 million people in the United States, and the ...
Mask face is a common symptom of Parkinson’s disease that can result in a mask-like expression that appears to lack emotion. Learn what causes this symptom, the ranges of severity, and how it ...
The progression of Parkinson’s is described in five stages. Stage 1 starts at the very beginning when the early signs start to appear. Stage 5 describes the final stage of the disease, when ...
Vascular Parkinsonism is a condition related to your vascular system and shares some symptoms with Parkinson’s disease. Find out what causes vascular Parkinsonism, known risk factors, available ...
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