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  2. Primary sclerosing cholangitis (PSC) is a rare liver disease that affects the bile ducts. PSC is progressive, which means it gets worse over time. Treatment includes taking certain medications ...

  3. Primary sclerosing cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_sclerosing_cholangitis

    Primary sclerosing cholangitis ( PSC) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts, which normally allow bile to drain from the gallbladder. Affected individuals may have no symptoms or may experience signs and symptoms of liver disease, such as yellow discoloration ...

  4. Primary Biliary Cirrhosis Vs. Primary Sclerosing Cholangitis

    www.healthline.com/health/primary-biliary...

    Here are the treatment options for PBC and PSC. Primary biliary cirrhosis treatment. Medications are the primary treatments for PBC. Doctors often prescribe ursodiol to slow the progression of ...

  5. Primary Sclerosing Cholangitis: Symptoms, Causes, Treatment

    www.webmd.com/digestive-disorders/primary...

    PSC develops slowly. You may have it for years before you notice any symptoms. Some of the signs are: Fatigue. Itchy skin. Yellowish skin and eyes caused by a condition called jaundice. As PSC ...

  6. muscle pain. bone or joint pain. bloating (fluid in the stomach area) fat deposits ( xanthomas) in the skin around the eyes and eyelids. fat deposits in the elbows, knees, palms, and soles of the ...

  7. Cholestasis - Wikipedia

    en.wikipedia.org/wiki/Cholestasis

    Patients with PSC also face elevated risk of pancreatic and colorectal cancer. Therefore, regular screening is recommended. No drugs are currently approved for treating PSC specifically. Although commonly given, ursodeoxycholic acid at moderate doses failed to improve transplant-free survival in randomized controlled trials.

  8. Primary biliary cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_biliary_cholangitis

    Frequency. 1 in 3,000–4,000 people. Primary biliary cholangitis ( PBC ), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1] [2] [3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.

  9. Drugs and Chemicals That Cause Toxic Liver Disease - WebMD

    www.webmd.com/hepatitis/toxic-liver-disease

    Many over-the-counter (OTC) and prescription medications can cause toxic liver disease. OTC pain relievers: Acetaminophen ( Tylenol) Nonsteroidal anti-inflammatory drugs ( NSAIDs) such as Aleve ...