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WebMD explains what you need to know about primary sclerosing cholangitis, a potentially deadly disease of the bile ducts that can lead to serious liver damage.
Primary sclerosing cholangitis ( PSC) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts, which normally allow bile to drain from the gallbladder. Affected individuals may have no symptoms or may experience signs and symptoms of liver disease, such as yellow discoloration of the skin and eyes, itching, and abdominal pain.
Primary sclerosing cholangitis (PSC) is a rare liver disease that affects the bile ducts. PSC is progressive, which means it gets worse over time. Treatment includes taking certain medications ...
Primary biliary cholangitis (PBC), also called primary biliary cirrhosis, and primary sclerosing cholangitis (PSC) are characterized by the breakdown of your bile ducts.
Researchers have established a connection between primary sclerosing cholangitis (PSC) and ulcerative colitis (UC). PSC is a rare condition that causes scarring in the bile ducts of the liver.
PSC is a liver disease that damages your bile ducts. It’s progressive, meaning it gets worse over time. About 4 out of 5 people who have PSC also have inflammatory bowel disease.
Chronic cholestasis is a feature in primary sclerosing cholangitis (PSC). PSC is a rare and progressive cholestatic liver disease characterized by narrowing, fibrosis, and inflammation of intrahepatic or extrahepatic bile ducts, leading to reduced bile flow or formation (i.e., cholestasis).
Risk factors for cholangiocarcinoma include primary sclerosing cholangitis (an inflammatory disease of the bile ducts), ulcerative colitis, cirrhosis, hepatitis C, hepatitis B, infection with certain liver flukes, and some congenital liver malformations. [1] [3] [8] However, most people have no identifiable risk factors. [3] The diagnosis is suspected based on a combination of blood tests ...