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  2. Takeaway. Primary sclerosing cholangitis (PSC) is a rare liver disease that affects the bile ducts. PSC is progressive, which means it gets worse over time. Treatment includes taking certain ...

  3. Primary sclerosing cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_sclerosing_cholangitis

    Primary sclerosing cholangitis ( PSC) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts, which normally allow bile to drain from the gallbladder. Affected individuals may have no symptoms or may experience signs and symptoms of liver disease, such as yellow discoloration ...

  4. Primary Sclerosing Cholangitis: Symptoms, Causes, Treatment

    www.webmd.com/digestive-disorders/primary...

    Primary sclerosing cholangitis (PSC) is a disease that affects your bile ducts. Bile is a digestive fluid your Liver makes. The ducts let it flow from your liver to your gallbladder and finally to ...

  5. Primary Biliary Cirrhosis Vs. Primary Sclerosing Cholangitis

    www.healthline.com/health/primary-biliary...

    Here are the treatment options for PBC and PSC. Primary biliary cirrhosis treatment. Medications are the primary treatments for PBC. Doctors often prescribe ursodiol to slow the progression of ...

  6. Primary Biliary Cholangitis: Prognosis, Stages, and Symptoms

    www.healthline.com/health/primary-biliary-cirrhosis

    Primary biliary cholangitis, formerly primary biliary cirrhosis, is a disease caused by damage to bile ducts in the liver. Here's info on diagnosis, treatment, and more.

  7. Cholestasis - Wikipedia

    en.wikipedia.org/wiki/Cholestasis

    Chronic cholestasis is a feature in primary sclerosing cholangitis (PSC). PSC is a rare and progressive cholestatic liver disease characterized by narrowing, fibrosis, and inflammation of intrahepatic or extrahepatic bile ducts, leading to reduced bile flow or formation (i.e., cholestasis).

  8. What Is Primary Biliary Cholangitis? - WebMD

    www.webmd.com/digestive-disorders/primary...

    Primary biliary cholangitis (PBC) is a rare liver disease. It blocks and destroys bile ducts in the liver. Doctors used to call it “primary biliary cirrhosis.”. “Biliary” means bile. That ...

  9. Cholangiocarcinoma - Wikipedia

    en.wikipedia.org/wiki/Cholangiocarcinoma

    For inflammatory bowel disease patients with altered DNA repair functions, the progression from PSC to cholangiocarcinoma may be a consequence of DNA damage resulting from biliary inflammation and bile acids. Certain parasitic liver diseases may be risk factors as well.