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www .nm .org. Northwestern Medicine formerly Northwestern Memorial Healthcare, is a non-profit healthcare system affiliated with the Northwestern University Feinberg School of Medicine, in Chicago, Illinois. Members include research hospitals, acute care facilities, and academic centers. Northwestern Medicine's flagship hospital is the ...
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc ( MYC ), l-myc ( MYCL ), and n-myc ( MYCN ). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc .
The Myb gene family is named after the eponymous gene in Avian myeloblastosis virus. The viral Myb (v-Myb, P01104) recognizes the sequence 5'- Y AAC K G-3'. It causes myeloblastosis (myeloid leukemia) in chickens. [7] Compared to the normal animal cellular Myb (c-myb), v-myb contains deletions in the C-terminal regulatory domain, leading to ...
58805 Ensembl ENSG00000009950 ENSMUSG00000005373 UniProt Q9NP71 Q99MZ3 RefSeq (mRNA) NM_032951 NM_032952 NM_032953 NM_032954 NM_032994 NM_021455 NM_001359237 RefSeq (protein) NP_116569 NP_116570 NP_116571 NP_116572 NP_067430 NP_001346166 Location (UCSC) Chr 7: 73.59 – 73.62 Mb Chr 5: 135.12 – 135.17 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carbohydrate-responsive element ...
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Young has introduced the concept of transcriptional amplification and described how much of the gene control program in cancer cells is amplified by oncogenic transcription factors such as c-MYC. According to Young, most genes experience transcription initiation, [9] but it is the control of transcription elongation that plays key roles in cell ...
Cibola County is a county in the U.S. state of New Mexico. As of the 2020 census, the population was 27,172. [1] Its county seat is Grants. [2] It is New Mexico's youngest county, and the third youngest county in the United States, created on June 19, 1981, from the westernmost four-fifths of the formerly much larger Valencia County . Cibola ...
The N-myc internal ribosome entry site (IRES) is an RNA element found in the n-myc gene. The myc family of genes when expressed are known to be involved in the control of cell growth, differentiation and apoptosis. n-myc mRNA has an alternative method of translation via an internal ribosome entry site where ribosomes are recruited to the IRES ...