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Because VHL disease can cause tumors in many different parts of the body, not everyone will have the same symptoms. Your symptoms will be dictated by the size of your tumors and where they’re ...
Von Hippel–Lindau disease (VHL), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. [3] It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor ...
The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease, which is characterized by hemangioblastomas of the brain, spinal cord and retina. It is also associated with kidney and pancreatic lesions.
Kidney disease can affect your body’s ability to clean your blood, filter extra water out of your blood, and help control your blood pressure. It can also affect red blood cell production and ...
Having certain genetic conditions, such as von Hippel-Lindau disease or inherited papillary renal cell carcinoma Having a family history of kidney cancer. The risk is especially high in siblings.
Bilateral kidney cancer is typically more common in people who have a family history of kidney cancer or who have certain genetic conditions, such as von Hippel-Lindau disease or hereditary ...
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