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  2. Ozempic: 5 Reasons People Don’t Lose Weight on GLP-1 Drugs

    www.healthline.com/health-news/ozempic-glp-1...

    Takeaway. While many people will respond to Wegovy and Ozempic for weight loss, up to about 15% of people will not respond to the drugs. The reasons vary, from the need to make lifestyle tweaks ...

  3. GERD Not Responding to PPIs: What It Could Mean, Next Steps

    www.healthline.com/health/gerd/gerd-not...

    GERD is called “refractory” if it doesn’t respond to PPIs for at least 8–12 weeks.There are many reasons why GERD may not respond to PPIs. Here are some of the possible reasons.

  4. Isosorbide Mononitrate: Uses, Side Effects, and Treatments

    www.healthline.com/health/isosorbide-mononitrate

    Isosorbide mononitrate doesn’t undergo a first pass of your liver and lasts many hours longer before it’s eliminated. Isosorbide mononitrate relaxes your blood vessels and increases the supply ...

  5. When Statins Don’t Work: Reasons Why and What Else to Try

    www.webmd.com/cholesterol-management/cholesterol...

    If statins don’t work well enough, think about what you’re eating. Changes to your diet can help you lower your cholesterol. Avoid: Saturated fat, found in red meat, full-fat dairy products ...

  6. What Is Exocrine Pancreatic Insufficiency? - WebMD

    www.webmd.com/digestive-disorders/exocrine...

    8 min read. Exocrine pancreatic insufficiency (EPI) causes problems in how you digest food. Your pancreas doesn't make enough of the enzymes that your body needs to break down and absorb nutrients ...

  7. When Sleeping Pills Don’t Work: Next Steps - WebMD

    www.webmd.com/sleep-disorders/treatment...

    Think about it: You’re having trouble sleeping, so you worry about how you’re going to function the next day, and those worries keep you awake. The next day, you worry about whether you’ll ...

  8. Ozempic Plateau: Why Weight Loss Drugs May Stop Working for You

    www.healthline.com/health-news/ozempic-plateau...

    Interest in semaglutide, the generic name for Ozempic and Wegovy, spiked in 2023. Clinical trials indicated that, with these drugs, people can lose an average of 15% of their body weight. However ...

  9. Migraine Medications Don't Work? Here's What to Do - WebMD

    www.webmd.com/.../migraine-treatment-not-working

    Some oral medications that help prevent migraine are: Antidepressants such as amitriptyline. Anti-seizure drugs such as topiramate and valproate. Beta-blockers such as metoprolol tartrate and ...