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View/Edit Mouse. The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease, which is characterized by hemangioblastomas of the brain, spinal cord and retina. It is also associated with kidney and pancreatic lesions.
Von Hippel–Lindau disease (VHL), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. [3] It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor ...
Because VHL disease can cause tumors in many different parts of the body, not everyone will have the same symptoms. Your symptoms will be dictated by the size of your tumors and where they’re ...
The ELST has been referred to as adenocarcinoma of endolymphatic sac, Heffner tumor, [1] papillary adenomatous tumor, aggressive papillary adenoma, invasive papillary cystadenoma, and papillary tumor of temporal bone. However, these names are not encouraged as they do not accurately classify the current understanding of the tumor. [2][3]
A hemangioblastoma tends to press against the cerebellum and brainstem. Common symptoms of one include: Headache. Loss of coordination. Imbalance. Nausea. Vomiting. The cerebellum is a small area ...
Hemangioblastomas, or haemangioblastomas, are vascular tumors of the central nervous system that originate from the vascular system, usually during middle age. Sometimes, these tumors occur in other sites such as the spinal cord and retina. [1] They may be associated with other diseases such as polycythemia (increased blood cell count ...
The All-Russian Hockey League (VHL) [1] [2] (Russian: Всероссийская хоккейная лига (ВХЛ), Vserossiyskaya hokkeinaya liga (VHL)), also known as the Major Hockey League [3] [4] or Higher Hockey League (HHL), [5] is a professional ice hockey league in Eurasia, and the second highest level of Russian hockey.
Central Italy encompasses four of the country's 20 regions: . Lazio; the Marches (Marche); Tuscany (Toscana); Umbria; The easternmost and southernmost parts of Lazio (Cittaducale, Amatrice, Sora, Cassino, Isola del Liri, Sperlonga, Fondi, Gaeta and Formia districts, as well as the islands of Ponza and Ventotene) are sometimes connected to Southern Italy (the so-called Mezzogiorno) for cultural ...