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Von Hippel–Lindau disease ( VHL ), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. [3] It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor ...
The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease, which is characterized by hemangioblastomas of the brain, spinal cord and retina. It is also associated with kidney and pancreatic lesions.
HIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in Physiology or Medicine 2019 was awarded for the discovery of HIF. HIF1A is a basic helix-loop-helix PAS domain containing ...
Hemangioblastoma are among the rarest central nervous system tumors, accounting for less than 2%. Hemangioblastomas usually occur in adults, yet tumors may appear in VHL syndrome at much younger ages. Men and women are approximately at the same risk.
This regimen is approved for hepatitis C genotype 3. It’s not approved to treat genotype 2, but doctors can use it off-label for certain people with this genotype. The dose is one daclatasvir ...
Official website. www .vhlru .ru /en /. The All-Russian Hockey League (VHL) [1] [2] (Russian: Всероссийская хоккейная лига (ВХЛ), Vserossiyskaya hokkeinaya liga (VHL) ), also known as the Major Hockey League [3] [4] or Higher Hockey League ( HHL ), [5] is a professional ice hockey league in Eurasia, and the second ...
Dynasty. 19th Dynasty. Ramesses II [a] ( / ˈræməsiːz, ˈræmsiːz, ˈræmziːz /; Ancient Egyptian: rꜥ-ms-sw, Rīꜥa-masē-sə, [b] Ancient Egyptian pronunciation: [ɾiːʕamaˈseːsə]; c. 1303 BC – 1213 BC ), [7] commonly known as Ramesses the Great, was an Egyptian pharaoh. He was the third ruler of the Nineteenth Dynasty.
The Virtual Health Library (VHL) ( Biblioteca Virtual en Salud, BVS) is an institution that employs the World Wide Web to "improve access to reliable, locally relevant information [on health and health sciences] for health-professionals, researchers, academics, educators, decision makers, and the general public". [1]