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Cadherin-1 is a classical member of the cadherin superfamily. The encoded protein is a calcium-dependent cell–cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid, and ovarian ...
T-cadherin, also known as cadherin 13, H-cadherin (heart), and CDH13, is a unique member of the cadherin superfamily of proteins because it lacks the transmembrane and cytoplasmic domains common to all other cadherins and is instead anchored to the cell's plasma membrane by the GPI anchor. Unlike classical cadherins, which are necessary for ...
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.
Congenital diaphragmatic hernia ( CDH) is a birth defect of the diaphragm. The most common type of CDH is a Bochdalek hernia; other types include Morgagni hernia, diaphragm eventration and central tendon defects of the diaphragm. Malformation of the diaphragm allows the abdominal organs to push into the chest cavity, hindering proper lung ...
Bones are as you know very rigid tissues so we have to utilize mechanical tools to prepare them properly to receive the implant. With respect to hip replacements, the materials have improved ...
Identify possible conditions and treatment related to your symptoms. This tool does not provide medical advice. NEW: This symptom checker now includes the ability to select symptoms by body location. We hope this makes it easier for you to identify your symptoms and possible conditions. The tool also allows you to select multiple symptoms quickly.
CDH16. Cadherin-16 is a protein that in humans is encoded by the CDH16 gene. [5] [6] [7] This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q 22.1, the gene localizes with superfamily members CDH1 ...
Function. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.