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CTLs are able to eliminate most cells in the body since most nucleated cells express class I MHC molecules. The CTL-mediated immune system can be divided into two phases. In the first phase, functional effector CTLs are generated from naive T c cells through activation and differentiation. In the second phase, affector CTLs destroy target cells ...
Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.. A cytotoxic T cell (also known as T C, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8 + T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens (such as viruses or bacteria), or ...
1997–present. Number built. 900+. Variants. Flight Design MC. The Flight Design CT series is a family of high-wing, tricycle undercarriage, two seat, ultralight and light-sport aircraft produced by Flight Design (Flightdesign Vertrieb) of Germany. The family includes the original CT and the CT2K, CTSW, CTLS and the MC models. [1]
Marmon-Herrington CTLS tanks (a CTLS-4TAC in the foreground and a CTLS-4TAY in the background) in Alaska, summer of 1942. The Marmon-Herrington Combat Tank Light Series were a series of American light tanks / tankettes that were produced for the export market at the start of the Second World War. The CTL-3 had a crew of two and was armed with ...
Tetramer assay. A tetramer assay (also known as a tetramer stain) is a procedure that uses tetrameric proteins to detect and quantify T cells that are specific for a given antigen within a blood sample. [1] The tetramers used in the assay are made up of four major histocompatibility complex (MHC) molecules, which are found on the surface of ...
Priming (immunology) Priming is the first contact that antigen-specific T helper cell precursors have with an antigen. It is essential to the T helper cells' subsequent interaction with B cells to produce antibodies. [1] Priming of antigen-specific naive lymphocytes occurs when antigen is presented to them in immunogenic form (capable of ...
CTL* is a superset of computational tree logic (CTL) and linear temporal logic (LTL). It freely combines path quantifiers and temporal operators. Like CTL, CTL* is a branching-time logic. The formal semantics of CTL* formulae are defined with respect to a given Kripke structure .
Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are potential candidates for use in cancer therapy. The field of cancer immunology studies such topics.