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  2. Primary sclerosing cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_sclerosing_cholangitis

    Primary sclerosing cholangitis (PSC) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts, which normally allow bile to drain from the gallbladder. Affected individuals may have no symptoms or may experience signs and symptoms of liver disease, such as yellow discoloration ...

  3. Takeaway. Primary sclerosing cholangitis (PSC) is a rare liver disease that affects the bile ducts. PSC is progressive, which means it gets worse over time. Treatment includes taking certain ...

  4. Primary Biliary Cirrhosis Vs. Primary Sclerosing Cholangitis

    www.healthline.com/health/primary-biliary...

    Summary. Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, and primary sclerosing cholangitis (PSC) both involve the breakdown of your bile ducts. Both conditions are ...

  5. Primary Sclerosing Cholangitis: Symptoms, Causes, Treatment

    www.webmd.com/digestive-disorders/primary...

    PSC develops slowly. You may have it for years before you notice any symptoms. Some of the signs are: Fatigue. Itchy skin. Yellowish skin and eyes caused by a condition called jaundice. As PSC ...

  6. Primary biliary cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_biliary_cholangitis

    Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1][2][3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis. Further slow damage to the liver tissue ...

  7. Cholestasis - Wikipedia

    en.wikipedia.org/wiki/Cholestasis

    PSC predominantly affects males (60–70%) of 30–40 years of age. [40] The disease has an incidence is 0.4–2.0 cases/100,000 and a prevalence of 16.2 cases/100,000, making it a rare disease. [42] [40] Nonetheless, PSC accounts for 6% of liver transplants in the US due to its eventual progression to end-stage liver disease, with a mean ...

  8. Chronic Liver Disease: Causes, Diagnosis, and Treatment

    www.healthline.com/health/chronic-liver-disease

    People with cirrhosis are at risk of developing end stage liver failure or liver cancer. Chronic liver disease can be caused by: high alcohol consumption over many years. hepatitis and other viral ...

  9. Primary Biliary Cholangitis: Symptoms, Causes, Diagnosis ...

    www.webmd.com/digestive-disorders/primary...

    Later, you might feel tired or have itchy skin or dry eyes and mouth. As the disease gets worse, you might notice: Yellow skin and eyes (jaundice) Swollen feet and ankles. Pain and swelling in ...