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Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and mediator of many leukocyte functions, platelet aggregation and degranulation, inflammation, and anaphylaxis. It is also involved in changes to vascular permeability, the oxidative burst ...
Platelet-activating factor receptor. The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. [5] [6] It is encoded in the human by the PTAFR gene. The PAF receptor shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF).
Lipoprotein-associated phospholipase A 2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A 2 enzyme that in humans is encoded by the PLA2G7 gene. [5][6] Lp-PLA 2 is a 45-kDa protein of 441 amino acids. [7] It is one of several PAF acetylhydrolases.
Paroxysmal AFib is an episode of an arrhythmia called atrial fibrillation. It results in uncoordinated movement of the atria before they return to sinus rhythm, which is the normal coordinated rhythm.
Atrial fibrillation (AFib) is a type of irregular heartbeat. If you have it, your doctor will classify yours by the reason for it and on how long it lasts. When your heartbeat returns to normal ...
The enzyme phospholipase A2 (EC 3.1.1.4, PLA2, systematic name phosphatidylcholine 2-acylhydrolase) catalyses the cleavage of fatty acids in position 2 of phospholipids, hydrolyzing the bond between the second fatty acid "tail" and the glycerol molecule: phosphatidylcholine + H 2 O = 1-acylglycerophosphocholine + a carboxylate.
Stages. Acute limb ischemia. Progression. Early symptoms. Treatment. Takeaway. PAD typically onsets with no noticeable symptoms. Over time, it can progress and begin causing limb pain and cramping ...
5737 19220 Ensembl ENSG00000122420 ENSMUSG00000028036 UniProt P43088 P43117 RefSeq (mRNA) NM_000959 NM_001039585 NM_008966 RefSeq (protein) NP_000950 NP_001034674 NP_032992 Location (UCSC) Chr 1: 78.3 – 78.54 Mb Chr 3: 151.5 – 151.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Prostaglandin F receptor (FP) is a receptor belonging to the prostaglandin (PG) group of receptors ...