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View/Edit Mouse. The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease, which is characterized by hemangioblastomas of the brain, spinal cord and retina. It is also associated with kidney and pancreatic lesions.
Von Hippel–Lindau disease (VHL), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. [3] It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor ...
Fray Luis de León 's classroom. The University of Salamanca (Spanish: Universidad de Salamanca) is a Spanish public research university, located in Salamanca, in the autonomous community of Castile and León. It was founded in 1218 by King Alfonso IX. It is the oldest university in the Hispanic world and one of the oldest in the world in ...
Around 20% to 25% of hemangioblastoma cases are caused by VHL. It affects 1 in 36,000 people. Hemangioblastomas are usually single tumors. Multiple tumors can appear. But that typically happens ...
www.vhlru.ru /en /. The All-Russian Hockey League (VHL)[1][2] (Russian: Всероссийская хоккейная лига (ВХЛ), Vserossiyskaya hokkeinaya liga (VHL)), also known as the Major Hockey League[3][4] or Higher Hockey League (HHL), [5] is a professional ice hockey league in Eurasia, and the second highest level of Russian hockey.
This is a very rare tumor, since only about 1 in 35,000 to 40,000 people have VHL, of whom about 10% have endolymphatic sac tumors. Patients usually present in the 4th to 5th decades without an gender predilection. The tumor involves the endolymphatic sac, a portion of the intraosseous inner ear of the posterior petrous bone. [1] [5]
Paella (/ paɪˈɛlə /, [1] / pɑːˈeɪjə /, [2] py-EL-ə, pah-AY-yə, Valencian: [paˈeʎa]; Spanish: [paˈeʝa]) is a rice dish originally from the Valencian Community. Paella is regarded as one of the community's identifying symbols. [3][4] It is one of the best-known dishes in Spanish cuisine. The dish takes its name from the wide ...
The Ciudad Mitad del Mundo (Middle of the World City) is a tract of land owned by the prefecture of the province of Pichincha, Ecuador. It is located at San Antonio parish of the canton of Quito, 26 km (16 mi) north of the center of Quito. The grounds contain the Monument to the Equator, which highlights the exact location of the Equator (from ...