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Glutathione synthetase ( GSS) ( EC 6.3.2.3) is the second enzyme in the glutathione (GSH) biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione. [2] Glutathione synthetase is also a potent antioxidant.
Glutamate–cysteine ligase (GCL) EC 6.3.2.2 ), previously known as γ-glutamylcysteine synthetase (GCS), is the first enzyme of the cellular glutathione (GSH) biosynthetic pathway that catalyzes the chemical reaction : L -glutamate + L -cysteine + ATP γ-glutamyl cysteine + ADP + P i. GSH, and by extension GCL, is critical to cell survival.
Glutathione peroxidase ( GPx) ( EC 1.11.1.9) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. [2] The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide ...
Some research suggests that this range should actually be more like 0.45 to 2.5 mIU/L. The TSH range may also vary slightly based on the testing facility where your blood is being analyzed. TSH ...
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Subclinical hyperthyroidism is when you have low levels of TSH but normal levels of T3 and T4. T4 (thyroxine) is a major hormone secreted by your thyroid gland. T3 (triiodothyronine) is a modified ...
The Bottom Line. Hypothyroidism, or low thyroid, is a common disorder. It can cause a variety of symptoms, such as fatigue, weight gain and feeling cold. It can also result in problems with your ...
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