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Endocrinology. Pyruvate dehydrogenase deficiency (also known as pyruvate dehydrogenase complex deficiency or PDCD or PDH deficiency) is a rare neurodegenerative disorder associated with abnormal mitochondrial metabolism. PDCD is a genetic disease resulting from mutations in one of the components of the pyruvate dehydrogenase complex (PDC). [1]
United States Army. Headquarters. Fort Belvoir, Virginia, U.S. Parent agency. Office of the Administrative Assistant to the Secretary of the Army. Website. armypubs .army .mil /default .aspx. The Army Publishing Directorate ( APD) is the United States Army 's centralized publications and forms management organization. [1]
t. e. The Defense Health Agency ( DHA) is a joint, integrated combat support agency that enables the U.S. Army, U.S. Navy, and U.S. Air Force medical services to provide a medically ready force and ready medical force to Combatant Commands in both peacetime and wartime. The DHA is in charge of integrating clinical and business operations across ...
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial is an enzyme that in humans is encoded by the PDHA1 gene.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA.
Two mature PDHA proteins come together with two PDHB proteins to form a heterotetrameric E1 subunit. Crystal Structures allowed for a model in which the enzyme undergoes a 2-A shuttle-like motion of its heterodimers to perform the catalysis. The protein encoded by the human PDHA2 gene is part of the pyruvate dehydrogenase multienzyme complex ...
Pyruvate dehydrogenase (lipoamide) beta, also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1-B is an enzyme that in humans is encoded by the PDHB gene. [5] [6] The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to ...
3rd Medical Command Headquarters and Headquarters Company was constituted 21 December 1928, in the Regular Army as the 3rd Auxiliary Surgical Group. Activated 5 May 1942, at Fort Sam Houston, Texas . Reorganized and redesignated 1 August 1945, as the 896th Medical Professional Service.
Logo for the Integrated Personnel and Pay System - Army. Integrated Personnel and Pay System-Army ( IPPS-A) is a United States Army acquisition program that seeks to integrate human resources and pay for all Army Soldiers. It provides online tools and replaces older Army human resource systems. It also provides talent management capabilities ...