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ADP (company), an American provider of human resources management software and services; AdP, a German self-help organisation for patients who have undergone pancreatectomy; Association of Directory Publishers, an international trade organization for print and online directory publishers
Adenosine diphosphate ribose (ADPR) is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. [1] ADPR is created from cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adenine dinucleotide (NAD +) as a cofactor. [1] ADPR binds to and activates the TRPM2 ion channel. [2] ADPR is the most potent agonist of ...
The company was founded in 1983 by Scott Cook and Tom Proulx in Palo Alto, California. [12] [13] [14] [15]Intuit was conceived by Scott Cook, whose prior work at Procter & Gamble helped him realize that personal computers would lend themselves towards replacements for paper-and-pencil based personal accounting. [16]
ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [1] [2] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. [3] [4] Improper ADP-ribosylation has been implicated in some forms of cancer. [5]
ADP interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12, and P2X1), which leads to platelet activation. [14] P2Y1 receptors initiate platelet aggregation and shape change as a result of interactions with ADP. P2Y12 receptors further amplify the response to ADP and draw forth the completion of aggregation.
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