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Von Hippel–Lindau disease (VHL), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. [3] It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor ...
The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease, which is characterized by hemangioblastomas of the brain, spinal cord and retina. It is also associated with kidney and pancreatic lesions.
Renal angiomyolipomas and cysts are the most common manifestations of TSC involving the kidney. Renal disease is among the most common causes of early death in TSC. One study found that renal lesions were present in 80% of patients by a mean age of 10.5 years. [37] Renal cell carcinoma occurs in 2-5% of patients with TSC at a mean age of 28 ...
Early detection and intervention can help prevent complications. Stress management: Practice stress-reducing techniques such as deep breathing, meditation, or yoga. Stress can affect blood sugar ...
Other symptoms of neurogenic bladder include: Repeated urinary tract infections (UTIs) An urgent need to pee. Leaking urine (day or night) Having to pee often. Not being able to feel a full ...
One of the spleen’s main jobs is to filter your blood. It affects the number of red blood cells that carry oxygen throughout your body, and the number of platelets, which are cells that help ...
This infection affects your brain and spinal cord and can be very serious. Some other symptoms include fever, a stiff neck, vomiting, and headaches. This is a type of cancer that affects your ...
Levothyroxine is used to treat an underactive thyroid gland (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone ...