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Figure 2. PDE5 domains. The PDE5 enzyme has a molecular mass of 200 kDa and its active state is a homodimer. PDE5 consists of monomers and each contains two major functional domains: the regulatory domain (R domain) which is located in the N-terminal portion of the protein and the catalytic domain (C domain) located in the more C-terminal portion of the protein.
Dipeptidyl peptidase-4 inhibitor. Inhibitors of dipeptidyl peptidase 4 ( DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2 . The first agent of the class – sitagliptin – was approved by the FDA in 2006.
The New South Wales Department of Planning and Environment ( DPE) was a department of the New South Wales Government, responsible for effective and sustainable planning to support the growth in the state of New South Wales, Australia. It made plans based on evidence for the state's cities and regions, working with the community, business and ...
Education in Bangladesh is administered by the country's Ministry of Education. [4] The Ministry of Primary and Mass Education implements policies for primary education and state-funded schools at a local level. [5] Education in Bangladesh is compulsory for all citizens until the end of grade eight. [6]
Dual phase evolution ( DPE) is a process that drives self-organization within complex adaptive systems. [1] It arises in response to phase changes within the network of connections formed by a system's components. DPE occurs in a wide range of physical, biological and social systems. Its applications to technology include methods for ...
The New York City Department of Environmental Protection ( DEP) is the department of the government of New York City [2] that manages the city's water supply and works to reduce air, noise, and hazardous materials pollution. Under a 1.3 billion dollar budget, it provides more than 1.1 billion US gallons (4,200,000 m 3) of water each day to more ...
Percentage. 37.43%. 37.48%. Swing. 1.38%. 2.04%. Constituencies in the state. Constituencies in yellow and in pink represent seats reserved for Scheduled Castes and Scheduled Tribes respectively. The 2024 Indian general election in Assam was held from 19 April to 7 May 2024, to elect the 14 members of the 18th Lok Sabha.
BJP. Elected Chief Minister. N. Biren Singh. BJP. Legislative Assembly elections were held in Manipur from 28 February to 5 March 2022 in two phases, to elect 60 members of the Manipur Legislative Assembly. The results declared on 10 March 2022. The newly constituted assembly was named 12th Manipur Legislative Assembly .